With the exception of severe male infertility, 70% of the oocytes will become fertilized. In the case of severe male infertility, ICSI (pronounced ick-see) may be used to fertilize the eggs, instead of simply placing them in a culture dish. With ICSI, the embryologist will choose a healthy-looking sperm and inseminate the oocyte with the sperm using a special thin needle.
If you’re worried that you might be an infertile woman, don’t lose your hope. Be encouraged, and know that many women get pregnant even after being diagnosed with infertility. Know that there is a reason for what you’re going through. I trust God and I rely on His power, peace, and joy every day. I know there is a reason why we struggled with infertility – and perhaps the reason is so I could write about fertility and encourage couples like you to keep the faith.
Additionally, couples may turn to assisted reproductive technology, the most common of which is in vitro fertilization (IVF). Other techniques may include special injections or using a donor's eggs or sperm. Complications can sometimes occur, the most common being bleeding or infection; ovarian hyperstimulation syndrome, in which the ovaries become swollen and painful; and multiple pregnancies.
If you're not pregnant, you'll stop taking progesterone and likely get your period within a week. If you don't get your period or you have unusual bleeding, contact your doctor. If you're interested in attempting another cycle of in vitro fertilization (IVF), your doctor might suggest steps you can take to improve your chances of getting pregnant through IVF.

Disclaimer: The information you enter is not stored by CDC and is only used to estimate your chances of success. The IVF success estimator does not provide medical advice, diagnosis, or treatment. These estimates may not reflect your actual rates of success during ART treatment and are only being provided for informational purposes. Estimates are less reliable at certain ranges/values of age, weight, height, and previous pregnancy and ART experiences. Please see your doctor and/or healthcare provider for a personalized treatment plan that is best for you.
In males with hepatitis B, The Practice Committee of the American Society for Reproductive Medicine advises that sperm washing is not necessary in IVF to prevent transmission, unless the female partner has not been effectively vaccinated.[37][38] In females with hepatitis B, the risk of vertical transmission during IVF is no different from the risk in spontaneous conception.[38] However, there is not enough evidence to say that ICSI procedures are safe in females with hepatitis B in regard to vertical transmission to the offspring.[38]
Deciding whether to undergo in vitro fertilization, and how to try if the first attempt is unsuccessful, is an incredibly complicated decision. The financial, physical, and emotional toll of this process can be difficult. Speak with your doctor extensively to determine what your best options are and if in vitro fertilization is the right path for you and your family. Seek a support group or counselor to help you and your partner through this process.
Unlike the simpler process of artificial insemination -- in which sperm is placed in the uterus and conception happens otherwise normally -- IVF involves combining eggs and sperm outside the body in a laboratory. Once an embryo or embryos form, they are then placed in the uterus. IVF is a complex and expensive procedure; only about 5% of couples with infertility seek it out. However, since its introduction in the U.S. in 1981, IVF and other similar techniques have resulted in more than 200,000 babies.
^ Chavez-Badiola, Alejandro; Flores-Saiffe Farias, Adolfo; Mendizabal-Ruiz, Gerardo; Garcia-Sanchez, Rodolfo; Drakeley, Andrew J.; Garcia-Sandoval, Juan Paulo (10 March 2020). "Predicting pregnancy test results after embryo transfer by image feature extraction and analysis using machine learning". Scientific Reports. 10 (1): 4394. Bibcode:2020NatSR..10.4394C. doi:10.1038/s41598-020-61357-9. PMC 7064494. PMID 32157183.
This chart is US national average data on success rates per IVF cycle by female age for 2014. The dark blue line (triangles) shows pregnancy rates per cycle by age. The orange line (circles) shows live birth rates per cycle by age. The rate of singleton live births per cycle is shown by the light blue line. The difference between "pregnancy" rate and "live birth" rate is due to miscarriages.
Connect with your partner. Remember that he is also coping with secondary infertility along with you, and while your partner may be dealing with it differently, it can be extremely helpful to check in with each other emotionally. Set aside some time to talk about how your infertility problems are affecting each of you — that can help you both work through your emotions. Tired of talking about infertility or channeling all your collective energy into that second pregnancy? Plan a date night — totally unrelated to any baby-making duties. Since secondary infertility problems can take a toll on any relationship, date nights are needed now more than ever to keep the love and fun flowing. An added bonus: Since less stress often improves fertility, enjoying just being a couple could even increase your odds of achieving that second pregnancy.
Endometriosis and infertility are often related, but treating this pelvic inflammatory disorder can improve your chances of pregnancy. Here’s a description of what causes endometriosis, the symptoms of endometriosis, and what to do if you suspect you have this pelvic disorder. According to Harvard Medical School, endometriosis is responsible for many cases of infertility, there… Read More »Endometriosis and Infertility – How a Pelvic Disorder Affects Pregnancy

Complexity. IUI refers to one procedure. Prepared sperm is placed directly in the patient’s uterus when she is ovulating in order to aid fertilization. IUI may be performed in sync with a woman’s natural cycle or timed with fertility medications to stimulate ovulation. IVF, on the other hand, is a process which consists of several stages and requires more than one procedure: first the ovaries are stimulated using a series of fertility medications, then the patient undergoes egg retrieval in a day procedure under a mild anesthetic, then after embryos have been created and incubated in the lab, they are placed directly into her uterus in the embryo transfer procedure. Even with the use of fertility drugs, going through IUI is less physically demanding than undergoing IVF.
Undergo minor surgery to retrieve eggs. Following a round of injections, your doctor will determine the best date to retrieve eggs from the follicles of your ovaries. If you choose to use donor eggs, the retrieval process will occur with the donor, or the frozen eggs may be collected and used. A partner’s sperm or donor sperm will also be collected.
Vibratory stimulation or electric ejaculation: Vibratory stimulation is a painless and non-sedative procedure adapted to collect the sperms of men with spinal cord injuries who cannot experience natural ejaculation. Electric ejaculation is used for men who do not respond to vibratory stimulation process. The collected sperm is then transferred to the woman’s uterus for fertilization.
Only 30 percent of patients who receive 100 mg of Clomiphene a day will produce more than three follicles. Patients that produce less than than three follicles have about half the chance of getting pregnant than those that produce greater than three follicles. Patients that receive fertility medications but do not do an insemination have only half the success rates compared to those who do.
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